However, there are concerns that the rate of concomitant use of gastroprotective drugs in elderly NSAID users is too low. English Encyclopedia is licensed by Wikipedia (GNU). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Concomitant illnesses may make it more difficult for the treating physician to determine the diagnosis or treatment of the primary illness. These are imaging procedures in medicine that are performed after giving the patient an iodinated contrast medium (e.g. Chemotherapy for cancer applies as an example. At end of study only: Check this box if participant took no concomitant medication . The Number of Concomitant Drugs and the Safety of Direct Oral Anticoagulants in Routine Care Patients with Atrial Fibrillation. Boggle gives you 3 minutes to find as many words (3 letters or more) as you can in a grid of 16 letters. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Descriptive statistical analysis. In addition to producing side effects when combined, concomitant drugs can also block or slow another drug’s metabolism by interfering with the digestive pathway or excretion by the kidneys or the liver, thereby markedly increasing the blocked drug’s half-life. In the case of diabetes-associated concomitant illnesses, such as hypertension, cardiovascular disease and vascular diseases, they must be addressed along with the treatment for diabetes. They may also can lead to kidney damage. Examples thereof include excipients, lubricants, binders and disintegrators for solid preparations; and solvents, solubilizing aids, suspending agents, isotonic agents, buffers and soothing agents for liquid preparations. Purpose. Concomitant drugs refer to two or more drugs or medications taken at the same time. Contact Us Use of other drugs in combination with psychostimulants may influence either the acute effects of either drug, or the longer-term risks associated with psychostimulant use. This is often the case in medicine. However, if you don’t like your paper for some reason, you can always receive a refund. If the blocked drug remains in its active form, symptoms of an overdose of that medication may develop, despite the patient having taken the drugs exactly as ordered. If a drug abuser ingests or misuses two or more drugs, either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc, this is also called "concomitant drugs". Lettris is a curious tetris-clone game where all the bricks have the same square shape but different content. The most common drug combined with others in this type of concomitant drug abuse is alcohol. Certain medications and over the counter preparations may cause worsening of MG symptoms. Tips: browse the semantic fields (see From ideas to words) in two languages to learn more. Get XML access to fix the meaning of your metadata. For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs whereby two or more medications are administered literally at the same time for the sake of the patient’s health. Each square carries a letter.  |  Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 … Ad Change the target language to find translations. Concomitant drugs refer to two or more drugs or medications taken at the same time. The treatment of these other diseases has an effect on blood sugar levels, so the patient's usual diabetes treatment may have to be changed. Concomitant drugs are two or more drugs used or given at or almost at the same time (one after the other, on the same day, etc.). For this reason, doctors often ask patients what medications they are regularly taking with every office appointment, and pharmacists carefully monitor patients’ drug regimes. Mean concomitant drug use was 3.2 per patient/year. With a SensagentBox, visitors to your site can access reliable information on over 5 million pages provided by Sensagent.com. ○   Boggle. The influence of concomitant medications on hepatic and intestinal metabolism becomes more complicated when a drug, including a prodrug, is metabolized to one or more active metabolites. This type of concomitant use can be used to potentiate the desired effect of the medications, such as in the use of tranquilizers with sedatives. According to the NIDA, As the name suggests, stimulants increase alertness, attention, and energy, as well as elevate blood pressure, heart rate, and respiration. Privacy policy ○   Anagrams Concomitant drugs in medicine. Ethanol Nicotine ... Concomitant marijuana use may increase the pharmacologic and toxic effects of cocaine. To make squares disappear and save space for other squares you have to assemble English words (left, right, up, down) from the falling squares. Moons,1Arno W. Hoes,1Geert-Jan Geersing,1and Hendrika A. van den Ham2. The authors wanted to find out whether concomitant drug abuse (i.e. Find out more, an offensive content(racist, pornographic, injurious, etc. The co-administration of a concomitant drug of misuse appeared to be a feature rather than a risk factor per se in such deaths.[3]. Kind Code: A1 . an opiate plus another drug of misuse) leads to an increased number of acute accidental opiate-related deaths. English thesaurus is mainly derived from The Integral Dictionary (TID). Concomitant definition is - accompanying especially in a subordinate or incidental way. Chemotherapy for cancer applies as an example. Concomitant drugs is also a term recognized with drug abuse or recreational use of street drugs. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. The English word games are: Yet, another example of concomitant drugs could be tetracycline antibiotics taken with supplemental calcium, where the calcium is taken just once in the morning and the antibiotic is administered every 6 hours until completed. Intervention: Monitor for adverse reactions and reduce dosage of Paxil CR or other protein-bound drugs as warranted. How to use concomitant in a sentence. These 2 chemotherapy protocols are very similar in principle. If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken. Examples: warfarin: Drugs Metabolized by CYP2D6: Clinical Impact: You can feel safe while using our website. We do our best to make our customers satisfied with the result. In addition showing how in this case, “the same time” means “same day,” this example illustrates one of the negative effects of drugs taken concomitantly — side effects that occur in combination — as concomitant calcium use decreases the effectiveness of the antibiotics. Give contextual explanation and translation from your sites ! First example. A windows (pop-into) of information (full-content of Sensagent) triggered by double-clicking any word on your webpage. This is often the case in medicine. Carline J. van den Dries,1Sander van Doorn,1Patrick Souverein,2Romin Pajouheshnia,2Karel G.M. Ho… For example, the Phase 1b/IIa study of the biologically active compound which was conducted on patients with active and moderate rheumatoid arthritis (RA) when the study protocol allowed a stable concomitant treatment with low doses of oral corticosteroids, NSAIDs or non-biological disease – modifying antirheumatic drugs (DMARDs): Methotrexatum, Leflunomide, Chloroquine, Sulfasalazine. See if you can get into the grid Hall of Fame ! Cannabis levels seem to be unaffected by cocaine. different types of contrast X-rays, CTs, MRIs). Record all concomitant medications, including therapies given to treat adverse events. It is recommended that gastroprotective drugs (i.e. Over time, this information can reveal combined side effects from concomitant drugs. An integral aspect of the information they continue to collect is the other drugs a patient takes in addition to their own medication. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. The percentages of potential / possible DI between the DAAs and the concomitant drugs on the CNS were: 2.7% … The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven. The concomitant use of Zoloft with another drug that is highly bound to plasma protein may increase free concentrations of Zoloft or other tightly-bound drugs in plasma. Examples of drug-specific factors include their cytotoxic effect on cells, mechanisms of clearance, and concomitant use with other non-chemotherapeutic nephrotoxic agents. The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven.  | Last modifications, Copyright © 2012 sensagent Corporation: Online Encyclopedia, Thesaurus, Dictionary definitions and more. ), http://www.bccancer.bc.ca/HPI/ChemotherapyProtocols/default.htm. ○   Lettris You can also try the grid of 16 letters. The term has two contextual uses: as used in medicine or as used in drug abuse. This designation is used when 2 or more medicinal drugs are given either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc. Concomitant medication is combining two or more treatment regimes when treating diseases. We recruited 1,170 patients (mean age 60.1 years, 56.4% male). Letters must be adjacent and longer words score better. If a drug abuser ingests or misuses two or more drugs, either at the same time or almost at the same time, this is also called "concomitant drugs". Concomitant drugs refer to two or more drugs or medications taken at the same time. The designation concomitant drugs has two contextual uses: as used in medicine or as used in drug abuse. Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDS), other antiplatelet drugs, warfarin, and other anticoagulants may add to this risk. Examples of concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time. Carline J. van den Dries. Wikipedia Dictionaries. Add new content to your site from Sensagent by XML. Often, they monitor the kidney function and the hydration status of their patients during the imaging procedure, especially whenever a concomitant drug (that is harmful to the kidney) is being used.[2]. Most English definitions are provided by WordNet . ○   Wildcard, crossword Cautionary Drugs. Ro, Cookies help us deliver our services. Choose the design that fits your site. Drugs that may decrease insulin requirements include alcohol, anabolic steroids, aspirin, fenfluramine and monoamine oxidase inhibitors; there have been isolated reports of decreased insulin requirements with captopril, clofibrate, cyclophosphamide, guanethidine, mebendazole, methandienone and oxytetracycline. Company Information Concomitant drug therapy may alter insulin requirements. The authors showed that at least in the Sheffield area, intravenous (IV) administration of an opiate is the most consistent factor associated with drug abuse deaths. It is important to check with your doctor before starting any new medication including over the counter medications or preparations. Examples of Concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time. Concomitant Medications NCI CRF Standards: Round 3. Cathartics and laxatives increase the motility of the intestine or increase the bulk of feces. You can make sure yourself by using our Plagiarism Check service, This site is protected by wp-copyrightpro.com. Table 3-2: Examples of clinical inhibitors for P450-mediated metabolisms (for concomitant use clinical DDI studies and/or drug labeling) (03/06/2020) Strong inhibitors Moderate inhibitors Concomitant use of drugs affecting the renin-angiotensin system Combination therapy with two drugs affecting the renin-angiotensin system (ACE inhibitors, angiotensin-II receptor antagonists, and aliskiren is not recommended due to an increased risk of hyperkalaemia, hypotension, and renal impairment, compared to use of a single drug. The common examples are Headache > by profuse urination of Gelsemium, Coryza associated with polyurea of Cal carb, Pain with chilliness of puls, Prolapse and uterine affection which is > ted by crossing legs but with empty all gone sinking feeling in abdomen and less sexual desire of Sepia etc. By using our services, you agree to our use of cookies. If the patient is receiving a "concomitant" medicinal drug (prescribed to the patient by another physician), and the radiologist performing the imaging procedure is unaware of this, potentially harmful side-effects can occur and increase the risk of contrast medium-induced nephropathy (i.e. Examples: warfarin: Drugs Metabolized by CYP2D6 Concomitant drugs: lt;p|>|Concomitant drugs| are two or more |drugs| used or given at or almost at the same time (on... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most definitive collection ever assembled. Confidentiality Guaranteed misoprostol, proton pump inhibitors or high doses of histamine H2 receptor antagonists) be taken concomitantly to prevent NSAID-induced GI complications among older people. Learn more. The standard of care (sometimes also called the "gold standard") for the adjuvant treatment of stage III colon cancer is the FOLFOX chemotherapy protocol (used in Europe, Japan, Canada, and Australia) and respectively the FLOX chemotherapy protocol (used in the USA). The concomitant use of Paxil CR with another drug that is highly bound to plasma protein may increase free concentrations of Paxil CR or other tightly-bound drugs in plasma. Both consist of 3 medicinal drugs: a) Leucovorin (= folinic acid = calcium folinate), b) 5-Fluorouracil (= 5-FU), and c) Oxaliplatin. Concomitant definition: Concomitant is used to describe something that happens at the same time as another thing... | Meaning, pronunciation, translations and examples United States Patent Application 20050197376 . Concomitant use of clinical status; occurrence suspected, established nonsteroidal antiinflammatory drugs (NSAIDs) with or probable in well-controlled studies 3 Interaction causes minor effects; occurrence warfarin is one of the examples for pharmacodynamic suspected, established or probable in interaction. 100 examples: Disorganized attachment in early childhood : meta-analysis of precursors… Concomitant drugs . Examples of concomitant in a sentence, how to use it. Remember to tell any doctor or dentist about your MG diagnosis. Indication Alternately, a blocked drug may remain unable to reach its potent active metabolite and prove ineffective for the patient at a therapeutically prescribed and administered dosage. All the papers we provide are written from scratch and are free from plagiarism. Since these 3 medicinal drugs are "concomitant" to each other, such a constellation is called "concomitant drugs". The SensagentBox are offered by sensAgent. The Concomitant Medications module was one of the group of variables included in the third round of the CRF Harmonization and Standardization Initiative. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. All rights reserved. [1], Contrast imaging in medicine is another example. the risk damage to the kidneys). The web service Alexandria is granted from Memodata for the Ebay search. It is well known that such iodinated contrast media can lead to acute allergies in some patients. This designation is used when 2 or more medicinal drugs are given either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc. English Wikipedia - The Free Encyclopedia. Pharmaceutical companies continue to collect data on reported side effects of the medications they manufacture long after approval testing is complete. Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. In general, radiologists carefully ask their patients about other medicinal drugs they are "concomitantly" taking before the imaging procedure. The wordgames anagrams, crossword, Lettris and Boggle are provided by Memodata. Intervention: Monitor for adverse reactions and reduce dosage of Zoloft or other protein-bound drugs as warranted. Did You Know? Get XML access to reach the best products.  |  These substances can be beneficial in many ways and may be used to help individuals with learning or mental disorders become more focused and lead more productive lives. Stimulants are a class of drugs that all cause similar effects on the body and mind. Concomitant drugs Definition from Encyclopedia Dictionaries & Glossaries. None Medication . Conversely, street and recreational drugs are also often combined in opposition to the primary effect of each — so as to minimize the unpleasant or undesired side effects — such as the concomitant use of cocaine and alcohol. Therapeutic concomitant drugs often demonstrate negative side effects when taken in combination, as in the above example. For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs wher… concomitant definition: 1. something that happens with something else and is connected with it: 2. happening and connected…. Your personal information will stay completely confidential and will not be disclosed to any third party. Whether concomitant drug abuse leads to an increased number of deaths was scientifically analysed in Sheffield, UK. Graphical extrapolations of historical prevalence of FGM have shown a shift in the practice by gradual decline in infibulations and concomitant rise in clitoridectomies. Authors wanted to find out whether concomitant drug therapy may alter insulin requirements over the counter medications or.... Ethanol Nicotine... concomitant marijuana use may increase the pharmacologic and toxic effects of the intestine or increase motility! You agree to our use of street drugs recognized with drug abuse common drug combined with others in type... Different content new medication including over the counter preparations may cause worsening of MG.. Abuse is alcohol after approval testing is complete also a term recognized with drug abuse from Memodata for Ebay! 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